After trying to make a some quick Christmas cash at a medical testing facility, a hapless slacker turns everybody he crosses paths with into rage-fueled maniacs who share a single target—him.It's not uncommon for people to seem a little 'on-edge' come the holiday season, but for mild-mannered Howard Phillips, it just so happens that everyone else is suddenly running right over that edge with bloodshot eyes, foaming mouths, and unstoppable urges to kill...and they're running towards him.It could have something to do with the lack of shopping days left on the calendar, but Howard is betting that his recent visit to a medical testing facility is more likely to blame. Before he can find out what he took and how to stop it, he’ll need to go toe-to-toe, or fist-to-teeth, with every bloodlusting living thing he encounters.